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CDE Almería – Centro de Documentación Europea – Universidad de Almería

CDE Almería - Centro de Documentación Europea - Universidad de Almería

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H2020. Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing: Next generation organ-on-chip

Inicio » EU Calls and Awards » H2020. Nanotechnologies, Advanced Materials, Biotechnology and Advanced Manufacturing and Processing: Next generation organ-on-chip

18 de November de 2019

Organ-on-Chip’ (OoC) is a promising technology for achieving more effective in-vitro research in a broad range of life science sectors, including medicine and pharmacy, cosmetics, agriculture and food, and for chemical safety testing including regulatory testing.

Specific Challenge

More effective drug development, efficacy, and safety screening, would reduce the need for animal testing and clinical testing. Nevertheless, much more research and development is needed to develop more robust, automated and parallelised OoC technologies that are applicable in industry, with medium to high throughput capacity, reliability and repeatability, using validated and standardised tools and methods.

Scope

  • Multidisciplinary research for the development of Organ-on-Chip technologies able to mimic human organs and organ-systems, based on integrated platforms involving technologies such as: cell culturing (including multi-tissue or multi-organ arrangements), micro-fluidics, micro/nano-sensors, imaging, actuators, 3D bio-printing, modelling and simulation, bioinformatics;
  • Demonstrator applications involving modelling, diagnosis and therapy of human disease(s) of high and yet unmet medical need. The new devices should permit the simulation of body system processes under adverse conditions and in particular in disease states, healing and regeneration under mechanical stress and electrical stimulation, or immune responses, taking into account sex and gender differences, when relevant;
  • Industrial development/piloting towards improved robustness, reliability, scalability, parallelisation and standardisation of tools and methods, and providing interfaces to standard laboratory equipment;
  • Taking into account medical regulatory requirements.

The Commission considers that proposals requesting a contribution from the EU of between EUR 4 and 6 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.

Expected Impact

  • Verifiable progress in the application of Organ-on-Chip technologies for in-vitro research;
  • Reduction of the need for animal and clinical testing;
  • Lowering of barriers for application of Organ-on-Chip technology;
  • Improved competitiveness and attractiveness of the European biomedical and healthcare sector;
  • Increased awareness and knowledge about medical regulatory policies and requirements, especially by academics and SMEs.

Deadline

12 December 2019 at 17:00 Brussels time

More information

Call

Horizon2020

Publicaciones relacionadas:

EUREKA: Research, development and innovation projects Turkey – Spain Laboratory research by two male scientists in laboratory using a microscope and laboratory glassware for scientific researchH2020: BBI-RIA: Model the composition of bio-based residual streams and its evolution to optimise its management and processing miniatura de coche estilo "Mini", de color verde, sobre el suelo exteriorHorizon 2020: Horizon Prize – Cleanest Engine of the Future : FutureEnginePrize-01-2016 cinco bombillas cuelgan del techo19 positions of IberusTalent pre-doctoral Programme (H2020-MSCA-Cofund) in Agrofood and Health Technologies PRIMA 2020 Call: Partnership for research and innovation in the Mediterranean area

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Publicaciones relacionadas


EUREKA: Research, development and innovation projects Turkey – Spain


Laboratory research by two male scientists in laboratory using a microscope and laboratory glassware for scientific researchH2020: BBI-RIA: Model the composition of bio-based residual streams and its evolution to optimise its management and processing


miniatura de coche estilo "Mini", de color verde, sobre el suelo exteriorHorizon 2020: Horizon Prize – Cleanest Engine of the Future : FutureEnginePrize-01-2016


cinco bombillas cuelgan del techo19 positions of IberusTalent pre-doctoral Programme (H2020-MSCA-Cofund) in Agrofood and Health Technologies


PRIMA 2020 Call: Partnership for research and innovation in the Mediterranean area

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