Evolutionary Medical Genomics (EvoMG) is a MSCA Doctoral Network programme that pioneers an integrative approach combining Evolutionary Medicine and Medical Genomics to address critical health challenges. By combining evolutionary insights with state-of-the-art genomic tools, EvoMG-DN seeks to establish EvoMG as a structured and impactful discipline in Europe. The network aims to train the next generation of interdisciplinary researchers to unlock the full potential of evolutionary genomic approaches in healthcare. The consortium includes 22 participating organisations, and the Institute of Cancer Research (ICR), London, UK is one of the partner. The PhD studentship for this project will be funded via HORIZON-MSCA-2024-DN-01 award.
The student will work on the project “Towards non-invasive monitoring and prediction of cancer evolutionary dynamics from cfDNA” under the guidance of Prof. Trevor Graham at the ICR.
Project aims
- Develop a sequencing approach to detect mutations and methylation in cfDNA from cancer patients
- Build computational tools to interpret methylation profiles from cfDNA
- Use sequencing to reconstruct clonal dynamics through treatment and resistance
- Apply the new methodology to samples from large clinical cohorts.
Requirements
BSc (First or 2:1) or Master’s degree in a biological, computational or quantitative subject.
A strong interest in evolutionary approaches to medicine is essential, and willingness to engage in extensive mathematical and computational work. Experience in sequencing technologies, epigenetics, or computational modelling would be highly advantageous but is not essential. Motivation to work at the interface of academia and industry, and enthusiasm for translational applications of genomics, will be highly valued.
Only applicants who satisfy the following mobility rule are eligible to apply: Applicants must not have resided or carried out their main activity (work, studies, etc.) in the UK for more than 12 months in the 36 months immediately before their recruitment date.
Benefits
The candidate will receive a monthly salary of Euros 4,917 (subject to tax and National Insurance deductions), which includes both a living allowance and a mobility allowance, for a duration of 36 months. Additionally, candidates with a family may be eligible for a monthly family allowance of Euros 380 (also subject to tax and National Insurance deductions), provided they meet the eligibility criteria for the MSCA family allowance. In the fourth year of the PhD, the candidate will receive the standard ICR stipend rate.
Organization/Company – The Institute of Cancer Research.
Research field –Biological sciences » Biology
Research profile – First Stage Researcher (R1).
Country – United Kingdom.
Application Deadline – 16 Nov 2025 – 23:59 (Europe/London).
More information: Euraxess
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