Applications are invited from suitably qualified candidates for a fully funded (fees and stipend), full-time PhD position at the University College Dublin, Dublin, Ireland. University College Dublin is ranked within the top 1 % of higher education institutions world-wide. The project aims to develop in vitro drug discovery tumour models using appropriate human cells (e.g. breast cancer). State-of-the-art biofabrication (e.g. bioprinting, electrospinning, decellularisation) and cell culture (e.g. bioreactors, hypoxia chambers) technologies will be utilised. The produced three-dimensional models will be characterised using an array of biochemical, biophysical, biomechanical and biological methods. Various anticancer compounds will be screened to assess the efficiency of the model and to obtain new fundamental knowledge about the mechanisms of carcinogenesis.
The candidate should have a 1st or 2:1 Bachelor’s degree and a Master’s in biomedical engineering, tissue engineering, cell biology, biology, pharmacology, biochemistry, or in a related area. The ideal candidate should have experience in as many of the following techniques: scaffold fabrication and characterisation; cell culture; molecular biology; protein and gene analysis; immunohistochemistry; and histology. The candidate should have excellent communication and organisational skills; be highly motivated and passionate about developing new products; and have strong written, oral and interpersonal skills. The candidate should be able to work independently and as a part of team.
The successful candidate will be involved in: Scaffold fabrication and characterisation, including cell derived matrices development; Cell acquisition from human tissues; In vitro biophysical, biomechanical, biochemical, biological characterisation of the produced in vitro models; Anti-tumour drug screening; Conference and Meeting attendance and participation; Report and paper writing; Participation to training courses; Undergraduate teaching and/or laboratory demonstrations; Travel to project partners’ institutes; Other duties relevant to the post.
University College Dublin
Ireland › Dublin
Engineering › Biomedical engineering
29th April 2022