{"id":58776,"date":"2020-12-28T03:00:43","date_gmt":"2020-12-28T02:00:43","guid":{"rendered":"https:\/\/www.cde.ual.es\/?p=58776"},"modified":"2021-11-05T14:22:30","modified_gmt":"2021-11-05T13:22:30","slug":"postdoc-position-molecular-cellular-biologist-in-netherlands","status":"publish","type":"post","link":"https:\/\/www.cde.ual.es\/en\/postdoc-position-molecular-cellular-biologist-in-netherlands\/","title":{"rendered":"Postdoc position, Molecular &#038; Cellular Biologist in the Netherlands"},"content":{"rendered":"<h3><a href=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920.jpg\"><img decoding=\"async\" class=\"aligncenter wp-image-58781\" src=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920-300x150.jpg\" alt=\"Postdoc position, Molecular &amp; Cellular Biologist in Netherlands\" width=\"424\" height=\"212\" srcset=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920-300x150.jpg 300w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920-1024x512.jpg 1024w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920-768x384.jpg 768w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920-1536x768.jpg 1536w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2020\/12\/cells-1872666_1920.jpg 1920w\" sizes=\"(max-width: 424px) 100vw, 424px\" \/><\/a><\/h3>\n<h3>Description<\/h3>\n<p>Cardiovascular disease accounts for 31% of all global deaths.<\/p>\n<p>Over the past decades, effective treatment to reduce plasma cholesterol (driving this disease) has been developed but at the same time the worldwide pandemic of obesity and type 2 diabetes has increased the complexity of treating patients at increased risk of cardiovascular disease who also suffer from e.g. insulin resistance, increased risk of fatty liver disease, and cancer.<\/p>\n<p>Promising candidate genes will be studied further to increase our fundamental (mechanistic) understanding of lipoprotein biology, autophagy and lipophagy. This project will be driven by the need to increase our molecular understanding of human cardiometabolic disease.<\/p>\n<h3>Benefits<\/h3>\n<p>&#8211; Job duration: 1 year with possible extension for 1 more year.<br \/>\n&#8211; The position is full time, but part-time at 0.8 fte can be considered.<br \/>\n&#8211; Preferred starting data: between Jan 1st and March 1st, 2021.<\/p>\n<p>Your salary will be a maximum of \u20ac 4.615,- gross per month (scale 10), depending on your qualifications and relevant experience, based on a full-time appointment<\/p>\n<h3>Requirements<\/h3>\n<p>For this project, we need a skilled post-doctoral molecular and cellular biologist. The effort requires molecular biology skills such as generating plasmids and virus batches to target genes in the liver of Alb-Cas9 mice. It will also involve logistical skills to conduct large-scale mouse studies that need to be characterized shortly after transduction. The project will entail basic characterization of plasma and liver lipids at baseline and sacrifice, liver histology etc. When promising candidate genes are identified, the post-doc will lead in-depth investigations in the molecular mechanisms that underly the observed phenotypes. This may e.g. entail mRNA seq analysis, immunofluorescence and electron microscopy, pulse-chase experience. The postdoc will work with a dedicated team of technicians as well as PhD students which will require good communication skills. Candidates with a drive to understand molecular mechanism and a priori knowledge of lipid metabolism are very welcome to apply for this position.<\/p>\n<div class=\"description__paragraph paragraph\">\n<div class=\"longtext field-skills-qualifications\">\n<h3>Organisation<\/h3>\n<\/div>\n<\/div>\n<div class=\"row\">\n<div class=\"col-sm-8 col-sm-offset-2 col-md-6 col-md-offset-3\">\n<div id=\"bootstrap-fieldgroup-accordion--accordion-group\" class=\"panel-group bootstrap-fieldgroup-accordion\">\n<div class=\"panel panel-default required-fields expanded\">\n<div id=\"bootstrap-fieldgroup-accordion-item--requirements-0\" class=\"panel-collapse required-fields collapse in\" aria-expanded=\"true\">\n<div class=\"panel-body\">\n<div class=\"row\">\n<div class=\"col-xs-12 field-offer-requirements\">\n<div class=\"longtext field-specific-requirements\">\n<div class=\"row\">\n<div class=\"col-xs-12 col-sm-7 value field-company-institute inline\">\n<div class=\"row\">\n<div class=\"col-xs-12 col-sm-7 value field-company-institute inline\">\n<div class=\"row\">\n<div class=\"row\">\n<div class=\"col-xs-12 col-sm-7 value field-company-institute inline\">\n<div class=\"row\">\n<div class=\"col-xs-12 col-sm-7 value field-company-institute inline\">\n<div class=\"row\">\n<div class=\"col-xs-12 col-sm-7 value field-company-institute inline\">University Medical Centre Groningen (UMCG)<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3>Research Field<\/h3>\n<p>Medical sciences<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<h3>Location<\/h3>\n<\/div>\n<p>Netherlands \u203a Groningen<\/p>\n<h3>Deadline<\/h3>\n<p>14 January 2021<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<h3>More information<\/h3>\n<p><a href=\"https:\/\/euraxess.ec.europa.eu\/jobs\/588042\" target=\"_blank\" rel=\"noopener\">Euraxess<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Description Cardiovascular disease accounts for 31% of all global deaths. Over the past decades, effective treatment to reduce plasma cholesterol (driving this disease) has been developed but at the same time the worldwide pandemic of obesity and type 2 diabetes has increased the complexity of treating patients at increased risk of cardiovascular disease who also [&hellip;]<\/p>\n","protected":false},"author":101012,"featured_media":58781,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[366,4043,4046],"tags":[2516,409,848,1656],"class_list":{"0":"post-58776","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-eu-calls-and-awards","8":"category-euraxess-en","9":"category-health-science","10":"tag-biologist","11":"tag-call","12":"tag-euraxess-en","13":"tag-netherlands","14":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Postdoc position, Molecular &amp; Cellular Biologist in the Netherlands | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cde.ual.es\/en\/postdoc-position-molecular-cellular-biologist-in-netherlands\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Postdoc position, Molecular &amp; Cellular Biologist in the Netherlands | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda\" \/>\n<meta property=\"og:description\" content=\"Description Cardiovascular disease accounts for 31% of all global deaths. 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