{"id":156278,"date":"2025-01-24T03:00:03","date_gmt":"2025-01-24T02:00:03","guid":{"rendered":"https:\/\/www.cde.ual.es\/?p=156278"},"modified":"2025-01-23T13:31:49","modified_gmt":"2025-01-23T12:31:49","slug":"phd-i-nvestigate-nk-cells-and-bi-specific-reagents-in-hiv-cure-netherlands","status":"publish","type":"post","link":"https:\/\/www.cde.ual.es\/en\/phd-i-nvestigate-nk-cells-and-bi-specific-reagents-in-hiv-cure-netherlands\/","title":{"rendered":"PhD &#8211; I nvestigate NK cells and bi-specific reagents in HIV cure &#8211; Netherlands"},"content":{"rendered":"<p style=\"text-align: justify;\"><a href=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280.jpg\"><img decoding=\"async\" class=\"wp-image-156280 aligncenter\" src=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280.jpg\" alt=\"\" width=\"849\" height=\"566\" srcset=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280.jpg 1280w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280-300x200.jpg 300w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280-1024x682.jpg 1024w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280-768x512.jpg 768w\" sizes=\"(max-width: 849px) 100vw, 849px\" \/><\/a><\/p>\n<p style=\"text-align: justify;\">The Department of Immunology has state-of-the-art facilities and equipment that support basic and translational research. Erasmus MC is one of the largest academic medical centers in Europe providing an outstanding environment for research, education and patient care. Erasmus MC is located in Rotterdam, The Netherlands, an exciting and thriving urban environment.<\/p>\n<p style=\"text-align: justify;\">The PhD student will work in close collaboration with other work groups within Erasmus MC, as well as with other investigators of the Spiral project in the Netherlands and sub-Saharan Africa.<\/p>\n<p style=\"text-align: justify;\"><strong>Job description<\/strong><\/p>\n<ul style=\"text-align: justify;\">\n<li>Characterize phenotype and function of NK cells in individuals with different backgrounds (biological sex, ethnicity\/genetic background, age).<\/li>\n<li>Using molecular clones, produce HIV subtypes which will be used in the in vitro assays. Most of the experiments will be performed in a BSL-3 facility.<\/li>\n<li>Develop strategies to eliminate the HIV latent reservoir in HIV-infected patients using bi-specific reagents (BiKEs). Evaluate efficiency of BiKEs in inducing NK cell mediated killing of cells infected with HIV-1 subtype A,B, C and D using in vitro models of HIV infection as well as primary cells.<\/li>\n<li>Investigate the combination of different latency reversing agents (LRAs) and BiKEs on NK cell-mediated killing of cells infected with HIV-1 subtype A,B, C and D.<\/li>\n<\/ul>\n<div class=\"ecl-u-type-bold ecl-u-mb-m\" style=\"text-align: justify;\"><strong>Specific Requirements<\/strong><\/div>\n<div class=\"ecl\" style=\"text-align: justify;\">\n<ul>\n<li>Hold a master degree with strong background in the area of immunology and viral infections\/HIV.<\/li>\n<li>Experience with NK and T cell immunology, HIV infection and multicolor flow cytometry is a plus.<\/li>\n<li>Has team spirit since the candidate is expected to collaborate closely with scientists within the Erasmus MC as well as national and international collaborators.<\/li>\n<li>Highly motivated and enthusiastic about research into HIV cure.<\/li>\n<li>Excellent verbal and written English communication skills.<\/li>\n<\/ul>\n<div class=\"ecl-u-type-bold ecl-u-mb-m\"><span style=\"font-size: 14pt;\"><strong>Benefits<\/strong><\/span><\/div>\n<div class=\"ecl\">\n<ul>\n<li>You will receive a temporary position for 4 years. The gross monthly salary is \u20ac 3.017,- in the first year and increases to \u20ac 3.824,- in the 4th\u00a0year (scale OIO).<\/li>\n<li>Excellent fringe benefits, such as a 13th month that is already paid out in\u00a0November and an individual travel expense package.<\/li>\n<li>Pension insurance with ABP, we take care of approximately 2\/3 of the monthly contribution.<\/li>\n<li>Special benefits, such as an incompany physiotherapist and bicycle\u00a0repairer. There is also a gym where you can work on your fitness after\u00a0work.<\/li>\n<li>An international office which aids you in preparing for your arrival and stay.<\/li>\n<\/ul>\n<p><strong>More information <a href=\"https:\/\/euraxess.ec.europa.eu\/jobs\/310506\">Euroxess.<\/a><\/strong><\/p>\n<\/div>\n<\/div>\n<p style=\"text-align: justify;\">\n","protected":false},"excerpt":{"rendered":"<p>The Department of Immunology has state-of-the-art facilities and equipment that support basic and translational research. Erasmus MC is one of the largest academic medical centers in Europe providing an outstanding environment for research, education and patient care. Erasmus MC is located in Rotterdam, The Netherlands, an exciting and thriving urban environment. The PhD student will [&hellip;]<\/p>\n","protected":false},"author":101011,"featured_media":156282,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[4043,4046,4045],"tags":[405,460],"class_list":{"0":"post-156278","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-euraxess-en","8":"category-health-science","9":"category-science","10":"tag-investigation","11":"tag-phd","12":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PhD - I nvestigate NK cells and bi-specific reagents in HIV cure - Netherlands | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cde.ual.es\/?p=156285\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PhD - I nvestigate NK cells and bi-specific reagents in HIV cure - Netherlands | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda\" \/>\n<meta property=\"og:description\" content=\"The Department of Immunology has state-of-the-art facilities and equipment that support basic and translational research. Erasmus MC is one of the largest academic medical centers in Europe providing an outstanding environment for research, education and patient care. Erasmus MC is located in Rotterdam, The Netherlands, an exciting and thriving urban environment. The PhD student will [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cde.ual.es\/?p=156285\" \/>\n<meta property=\"og:site_name\" content=\"CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cdeuniversidadalmeria\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-24T02:00:03+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/analysis-2030265_1280-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"853\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"BECA 2 CDE\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@cdeualmeria\" \/>\n<meta name=\"twitter:site\" content=\"@cdeualmeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"BECA 2 CDE\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=156285#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=156285\"},\"author\":{\"name\":\"BECA 2 CDE\",\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/#\\\/schema\\\/person\\\/ee46ebc19edfa19598c02cff83335acc\"},\"headline\":\"PhD &#8211; 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