{"id":155841,"date":"2025-01-13T03:00:16","date_gmt":"2025-01-13T02:00:16","guid":{"rendered":"https:\/\/www.cde.ual.es\/?p=155841"},"modified":"2025-01-10T12:02:49","modified_gmt":"2025-01-10T11:02:49","slug":"funding-independent-healthcare-research-topics-that-industry-ignores","status":"publish","type":"post","link":"https:\/\/www.cde.ual.es\/en\/funding-independent-healthcare-research-topics-that-industry-ignores\/","title":{"rendered":"Funding independent healthcare research topics that industry ignores"},"content":{"rendered":"<p style=\"text-align: justify;\">EU-backed scientists explore why we need to support multinational clinical studies carried out by independent researchers, and how to do it.<\/p>\n<p style=\"text-align: justify;\"><a href=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280.jpg\"><img decoding=\"async\" class=\"wp-image-155836 aligncenter\" src=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280.jpg\" alt=\"\" width=\"696\" height=\"464\" srcset=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280.jpg 1280w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280-300x200.jpg 300w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280-1024x682.jpg 1024w, https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280-768x512.jpg 768w\" sizes=\"(max-width: 696px) 100vw, 696px\" \/><\/a><\/p>\n<p class=\"c-article__text \" style=\"text-align: justify;\">A new paper published in the journal \u2018Trials\u2019 takes a close look at investigator-initiated clinical studies (IICSs), non-commercial studies conducted by independent clinicians and researchers with the ultimate goal of improving healthcare. The result of work carried out under the EU-funded ERA4Health project, the paper discusses why we need to support multinational IICSs, what their objectives should be, the main barriers to implementation and current funding mechanisms in Europe.<\/p>\n<h2 class=\"c-article__title\" style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">The pros of multinational research<\/span><\/h2>\n<p class=\"c-article__text \" style=\"text-align: justify;\">Unlike industry-funded studies, which usually research products that can generate revenue for companies, IICSs \u2013 including investigator-initiated clinical trials (IICTs) \u2013 tackle important research questions usually neglected by industry. However, even though they account for almost half of current clinical research in Europe, IICTs are mostly carried out in a single country. So, what would happen if scientists took advantage of Europe\u2019s huge population size, medical expertise, high-quality healthcare systems and scientific potential through multinational cooperation in clinical studies? As stated in the paper, it \u201cwould boost clinical research and its impact in Europe,\u201d fostering rapid patient recruitment and spreading best practice. \u201cMultinational IICSs increase the scientific quality of the data by exchange of research ideas, scientific techniques and tools,\u201d the authors report, adding: \u201cParticipation of patients from different geographical, social and ethnic backgrounds equally adds to the value of study results and yields more generalisable evidence than a study confined to a single geographical location.\u201d<\/p>\n<h2 class=\"c-article__title\" style=\"text-align: justify;\"><span style=\"font-size: 14pt;\">Public funding barriers<\/span><\/h2>\n<p class=\"c-article__text \" style=\"text-align: justify;\">Clinical studies should focus on developing innovative health products, identifying new uses for approved medicines and comparing treatments with the goal of optimising them. They therefore need to be funded through well-financed multinational programmes. However, current multinational IICSs are usually sponsored by academic organisations and publicly funded, which is a key barrier to carrying out multinational IICSs, and especially IICTs. The main challenges identified include budget limitations and grant durations, lack of flexibility to move funds transnationally, tendering rules and the complexity in the reporting of eligible costs to funders. According to the authors, strategies for funding multinational IICSs should evolve to diminish the barriers outlined. This could be achieved by prioritising public funding towards multinational IICS objectives, by implementing flexible public funding across borders, and by sustaining clinical research infrastructures and networks. This could help promote research into important healthcare issues that are less likely to be tackled by the pharmaceutical and medical device industries. Some of the topics described in the paper were discussed in an earlier workshop hosted by project partner European Clinical Research Infrastructure Network, France. The workshop focused on funding mechanisms for multinational IICSs through joint transnational calls and served as a platform for stakeholders to exchange ideas, explore innovative funding solutions and lay the groundwork for better multinational IICS support. The ERA4Health (Fostering a European Research Area for Health Research) project has also recently published a Joint Transnational Call for Investigator-Initiated Clinical Studies, JTC IICS, 2025, titled \u201cFostering Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases\u201d (EffecTrial). The deadline for submission of pre-proposals is 28 January.<\/p>\n<p><strong>More information <a href=\"https:\/\/cordis.europa.eu\/article\/id\/455694-funding-independent-healthcare-research-topics-that-industry-ignores\">CORDIS.<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>EU-backed scientists explore why we need to support multinational clinical studies carried out by independent researchers, and how to do it. A new paper published in the journal \u2018Trials\u2019 takes a close look at investigator-initiated clinical studies (IICSs), non-commercial studies conducted by independent clinicians and researchers with the ultimate goal of improving healthcare. The result [&hellip;]<\/p>\n","protected":false},"author":101011,"featured_media":155836,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[4092,4096],"tags":[437,13163],"class_list":{"0":"post-155841","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"category-tech-prof-health","9":"tag-health","10":"tag-technological-developments","11":"entry"},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Funding independent healthcare research topics that industry ignores | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.cde.ual.es\/?p=155832\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Funding independent healthcare research topics that industry ignores | CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda\" \/>\n<meta property=\"og:description\" content=\"EU-backed scientists explore why we need to support multinational clinical studies carried out by independent researchers, and how to do it. 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The result [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.cde.ual.es\/?p=155832\" \/>\n<meta property=\"og:site_name\" content=\"CDE Almer\u00eda - Centro de Documentaci\u00f3n Europea - Universidad de Almer\u00eda\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/cdeuniversidadalmeria\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-01-13T02:00:16+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.cde.ual.es\/wp-content\/uploads\/2025\/01\/laboratory-563423_1280.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"853\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"BECA 2 CDE\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@cdeualmeria\" \/>\n<meta name=\"twitter:site\" content=\"@cdeualmeria\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"BECA 2 CDE\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832\"},\"author\":{\"name\":\"BECA 2 CDE\",\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/#\\\/schema\\\/person\\\/ee46ebc19edfa19598c02cff83335acc\"},\"headline\":\"Funding independent healthcare research topics that industry ignores\",\"datePublished\":\"2025-01-13T02:00:16+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832\"},\"wordCount\":524,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.cde.ual.es\\\/wp-content\\\/uploads\\\/2025\\\/01\\\/laboratory-563423_1280.jpg\",\"keywords\":[\"health\",\"TECHNOLOGICAL DEVELOPMENTS\"],\"articleSection\":[\"Health\",\"Technological and Professional Health\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832\",\"url\":\"https:\\\/\\\/www.cde.ual.es\\\/?p=155832\",\"name\":\"Funding independent healthcare research topics that industry ignores | CDE Almer\u00eda - 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